Acute psychosis or mania (in-patient setting)
To be used on an as required basis
Short duration of action
If the patient is prescribed a regular antipsychotic then lorazepam avoids the risks associated with combining antipsychotics.
| Pack | Price |
|---|---|
| 100 tablet | |
| 1000 tablet | |
| 28 tablet | £3.74 |
| 30 tablet | |
| 50 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £8.82 |
| 30 tablet |
For patients not already taking a regular oral or depot antipsychotic
Recommended PRN dose 2 - 5mg
Halve the dose if > 65 years old or learning disabilities
DO NOT USE if evidence of cardiovascular disease or if no recent normal ECG has been carried out
| Pack | Price |
|---|---|
| 30 capsule | £1.18 |
| Pack | Price |
|---|---|
| 100 tablet | |
| 1000 tablet | |
| 28 tablet | £11.20 |
| 30 tablet |
| Pack | Price |
|---|---|
| 100 tablet | |
| 250 tablet | |
| 28 tablet | £12.34 |
| 30 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £22.05 |
| Pack | Price |
|---|---|
| 100 tablet | |
| 20 tablet | |
| 28 tablet | £21.86 |
| 30 tablet | |
| 50 tablet |
| Pack | Price |
|---|---|
| 100 ml | £7.10 |
| 500 ml |
For patients not already taking a regular oral or depot antipsychotic
Recommended dose 5 - 10mg, minimum interval between doses 2 hours, maximum dose in 24 hours 20mg (10mg if >65 years old or learning disabilities)
Not to be given within 1 hour of intramuscular lorazepam
If used for greater than 48 hours review and consider prescribing regularly
| Pack | Price |
|---|---|
| 28 tablet | £6.91 |
| Pack | Price |
|---|---|
| 28 tablet | £15.00 |
| Pack | Price |
|---|---|
| 28 tablet | £12.10 |
| 56 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £35.87 |
| 56 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £26.35 |
| Pack | Price |
|---|---|
| 28 tablet | £46.50 |
| Pack | Price |
|---|---|
| 28 tablet | £20.18 |
| Pack | Price |
|---|---|
| 28 tablet | £34.83 |
| Pack | Price |
|---|---|
| 28 tablet | £34.81 |
| Pack | Price |
|---|---|
| 28 tablet | £49.74 |
| Pack | Price |
|---|---|
| 28 tablet | £37.24 |
| Pack | Price |
|---|---|
| 28 tablet | £66.76 |
| Pack | Price |
|---|---|
| 28 tablet | £58.01 |
| Pack | Price |
|---|---|
| 28 tablet | £96.14 |
For patients not already taking a regular oral or depot antipsychotic
Recommended PRN dose 50 - 100mg
If used for greater than 48 hours review and consider prescribing regularly
| Pack | Price |
|---|---|
| 30 tablet | |
| 6 tablet | |
| 60 tablet | £13.84 |
| Pack | Price |
|---|---|
| 2 tablet | |
| 60 tablet | £52.22 |
| Pack | Price |
|---|---|
| 2 tablet | |
| 60 tablet | £61.75 |
| Pack | Price |
|---|---|
| 60 tablet | £51.30 |
| Pack | Price |
|---|---|
| 60 tablet | £73.45 |
| Pack | Price |
|---|---|
| 60 tablet | £67.66 |
| Pack | Price |
|---|---|
| 60 tablet | £113.10 |
| Pack | Price |
|---|---|
| 60 tablet | £113.10 |
| Pack | Price |
|---|---|
| 60 tablet | £170.00 |
| Pack | Price |
|---|---|
| 60 tablet | £226.20 |
For patients not already taking a regular oral or depot antipsychotic
Recommended PRN dose 1 - 2mg
If used for greater than 48 hours review and consider prescribing regularly
| Pack | Price |
|---|---|
| 20 tablet | £0.59 |
| Pack | Price |
|---|---|
| 20 tablet | £0.61 |
| 6 tablet | |
| 60 tablet |
| Pack | Price |
|---|---|
| 60 tablet | £1.28 |
| Pack | Price |
|---|---|
| 20 tablet | |
| 60 tablet | £1.55 |
| Pack | Price |
|---|---|
| 20 tablet | |
| 60 tablet | £1.72 |
| Pack | Price |
|---|---|
| 28 tablet | £3.04 |
| 30 tablet | |
| 60 tablet |
| Pack | Price |
|---|---|
| 100 ml | £4.10 |
| Pack | Price |
|---|---|
| 28 tablet | £23.86 |
| Pack | Price |
|---|---|
| 28 tablet | £24.02 |
| Pack | Price |
|---|---|
| 28 tablet | £44.43 |
| Pack | Price |
|---|---|
| 28 tablet | £43.49 |
| Pack | Price |
|---|---|
| 28 tablet | £50.35 |
Prescribers are reminded to be alert to the risk of addictive gambling and other impulse control disorders. It is important to advise patients, their families and friends to be alert to these risks.
For patients not already taking a regular oral or depot antipsychotic
Recommended PRN dose 9.75mg
| Pack | Price |
|---|---|
| 1 vial |
Recommended dose 1 - 2 mg (0.5 - 1mg if >65 years or learning disability)
Ensure flumazenil available in case of benzodiazepine-induced respiratory depression
Repeat after 30 - 60 minutes if partial response
Maximum dose in 24 hours 4mg (2mg if >65 years or learning disability)
| Pack | Price |
|---|---|
| 10 ampoule |
Restricted to initiation by a consultant
For patients not already taking a regular oral or depot antipsychot
Recommended dose 5 - 10mg (2.5 - 5mg if > 65 years or learning disability)
Minimum interval between doses 2 hours, maximum dose in 24 hours 20mg (10mg if >65 years old or learning disabilities)
Not to be given within 1 hour of intramuscular lorazepam
| Pack | Price |
|---|---|
| 1 vial |
Recommended dose 50 mg (25 mg if >65 years old or learning disability) in combination with haloperidol
Maximum dose 100mg in 24 hours (50mg if >65 years old or learning disability)
Repeat after 30 - 60 minutes if partial response
Recommended in people known to have dependency on benzodiazepines
| Pack | Price |
|---|---|
| 10 ampoule |
For patients not already taking a regular oral or depot antipsychotic
Recommended dose 5 mg (2.5mg if >65 years or learning disability) in combination with i.m. promethazine
Maximum dose in 24 hours 20mg (5mg if > 65 years or learning disability)
Ensure i.m. procyclidine available
Repeat after 60 minutes if partial response. Continued use should be evaluated early in treatment
DO NOT USE if evidence of cardiovascular disease or if no recent normal ECG has been carried out (within a month)
| Pack | Price |
|---|---|
| 1 ampoule | |
| 10 ampoule | £35.00 |
| 5 ampoule |
Initiation by senior psychiatrist (ST4 and above)
Only to be used for the short term treatment of acute psychosis or mania if:
the patient has required repeated injections of a short acting antipsychotic
where a rapid onset of action and duration of effect of 2-3 days is desirable
giving repeated short acting antipsychotic injections would be inappropriate
the patient has had a previous good response and shown good tolerability to zuclopenthixol acetate
sufficient time has elapsed to assess the full response to previously injected drugs (30-60 mins after IM)
an advanced directive has been made indicating that this is a treatment of choice
KMPT Guidelines for the use of zuclopenthixol acetate injection
| Pack | Price |
|---|---|
| 5 ampoule | £24.21 |