Post-Traumatic Stress Disorder

Short term use of a hypnotic may be appropriate for management of sleep disturbance but consider use of a suitable antidepressant at an early stage for longer term management

Pack Price
30 capsule £57.34
Pack Price
28 capsule
30 capsule £0.80
Pack Price
28 tablet £3.44
Pack Price
70 ml £12.95
Pack Price
30 capsule £1.80
Pack Price
30 capsule £1.80
Pack Price
30 capsule £6.66

Women of child-bearing potential must use adequate contraception

High potential for withdrawal symptoms, other SSRIs are preferred

Pack Price
28 tablet £9.31
Pack Price
14 tablet
28 tablet
30 tablet £1.26
Pack Price
30 tablet £1.53
Pack Price
28 tablet
30 tablet
Pack Price
150 ml £9.12

N.B Do not prescribe 25mg, 150mg or 200mg tablets. 50mg tablets can be halved.

Pack Price
14 tablet
28 tablet £1.06
30 tablet
Pack Price
28 tablet £0.89
30 tablet
Pack Price
28 tablet
56 tablet £2.05
60 tablet
Pack Price
42 tablet
Pack Price
28 tablet
56 tablet £3.48
60 tablet
Pack Price
28 capsule £5.25
Pack Price
30 tablet £6.60
Pack Price
14 capsule
28 capsule £2.60
30 capsule
Pack Price
28 tablet
30 tablet £2.60
Pack Price
14 capsule
28 capsule £3.90
30 capsule
Pack Price
28 tablet
30 tablet £3.90
Pack Price
28 capsule £47.11
30 capsule
Pack Price
28 tablet
30 tablet £33.60

Not licensed for this indication but recommended by NICE CG26

Recommended dose initially 75mg (ELDERLY 30mg - 75mg)daily in divided doses or as a single dose at bedtime increased gradually as necessary to 150mg - 200mg

Pack Price
28 tablet £1.05
Pack Price
28 tablet £0.88
500 tablet
Pack Price
28 tablet £2.20
Pack Price
150 ml £18.00
Pack Price
150 ml £19.20

Not licensed for this indication but recommended by NICE CG26

Recommended dose initially 15-30mg at bedtime increased within 2-4 weeks according to response. Maximum 45mg daily as a single dose at bedtime or in 2 divided doses

Pack Price
28 tablet £2.84
30 tablet
Pack Price
28 tablet £1.22
30 tablet
Pack Price
28 tablet £2.77
30 tablet
Pack Price
30 tablet £1.24
6 tablet
Pack Price
30 tablet £1.34
Pack Price
30 tablet £1.79
Pack Price
30 tablet
Pack Price
30 tablet
Pack Price
1 ml

Not licensed for this indication but recommended by NICE CG26

Patient must be informed of dietary restrictions and drug interactions (see SPC and / or BNF for details)

Recommended dose initially 15mg 3 time a day, increased if necessary to 4 times a day after 2 weeks (hospital patients max 30mg 3 times a day), then reduced gradually to lowest possible maintenance dose

Phenelzine 15mg tablets are not available, click here for more information

Pack Price
100 tablet £22.50

Not licensed for this indication but recommended by NICE CG26

Unlicensed for this indication but recommended by Maudsley

Antipsychotics have been found to be effective for the intrusion symptoms (flashbacks and nightmares) but not the avoidance and hyperarousal symptoms of PTSD. May be used as monotherapy or adjunctive therapy.

Plasma level reduced by up to 50% by cigarette smoke

Recommended dose initially 10mg adjusted as necessary to 5 - 20mg 
  
Plasma concentration monitoring form ONLY for diagnosis of acute poisoning  

Pack Price
28 tablet £6.91
Pack Price
28 tablet £15.00
Pack Price
28 tablet £12.10
56 tablet
Pack Price
28 tablet £35.87
56 tablet
Pack Price
28 tablet £26.35
Pack Price
28 tablet £46.50
Pack Price
28 tablet £20.18
Pack Price
28 tablet £34.83
Pack Price
28 tablet £34.81
Pack Price
28 tablet £49.74
Pack Price
28 tablet £37.24
Pack Price
28 tablet £66.76
Pack Price
28 tablet £58.01
Pack Price
28 tablet £96.14

Antipsychotics have been found to be effective for the intrusion symptoms (flashbacks and nightmares) but not the avoidance and hyperarousal symptoms of PTSD. May be used as monotherapy or adjunctive therapy.

Unlicensed for this indication but recommended by Maudsley

Dose 50 - 800mg

Pack Price
2 tablet
60 tablet £5.09
Pack Price
60 tablet £113.10
Pack Price
2 tablet
60 tablet £5.64
Pack Price
60 tablet £113.10
Pack Price
60 tablet £5.46
Pack Price
30 tablet
6 tablet
60 tablet £1.67
Pack Price
60 tablet £170.00
Pack Price
60 tablet £6.39
Pack Price
60 tablet £226.20
Pack Price
60 tablet £67.66

Antipsychotics have been found to be effective for the intrusion symptoms (flashbacks and nightmares) but not the avoidance and hyperarousal symptoms of PTSD. May be used as monotherapy or adjunctive therapy.

Unlicensed for this indication but recommended by Maudsley

Dose 0.5 - 6mg

Pack Price
28 tablet £21.75
Pack Price
20 tablet £0.90
6 tablet
60 tablet
Pack Price
100 ml £3.33
Pack Price
28 tablet £39.95
Pack Price
60 tablet £1.37
Pack Price
28 tablet £43.50
Pack Price
20 tablet
60 tablet £1.61
Pack Price
28 tablet £50.27
Pack Price
20 tablet
60 tablet £13.86
Pack Price
28 tablet £23.86
Pack Price
20 tablet £1.10
Pack Price
28 tablet £39.92
30 tablet
60 tablet

Restricted to initiation by specialists

Not licensed for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

An ECG and BP recording should be taken before commencing treatment for people at significant risk of cardiovascular disease

Recommended dose initially 25mg daily (ELDERLY 10mg daily) increased over 2 weeks to 100mg - 150mg daily, maximum dose 250mg daily

Pack Price
100 capsule
28 capsule £1.28
84 capsule
Pack Price
100 capsule
28 capsule £1.48
84 capsule
Pack Price
100 capsule
28 capsule £1.70
56 capsule

Restricted to initiation by specialists

The Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Recommended dose initially 30mg once daily increased if necessary to 60mg once daily

Pack Price
28 capsule £2.66
56 capsule
Pack Price
28 capsule £1.77
Pack Price
56 capsule £5.52
Pack Price
28 capsule £2.40
84 capsule

Restricted to initiation by specialists

The Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Recommended dose: initially 0.5mg 2 - 3 times a day with the first dose at night time, increase after 3 - 7 days to 1mg 2 - 3 times daily for a further 3 - 7 days. Increased to a maximum of 20mg daily in divided doses. Effective dose in clinical trial was 10 - 15mg daily.

Pack Price
56 tablet
60 tablet £2.69
8 tablet
Pack Price
32 tablet
56 tablet
60 tablet £3.46
Pack Price
1 tablet
100 tablet
56 tablet