Obsessive Compulsive Disorder

Not licensed for OCD but recommended by NICE CG31

Not licensed for this indication but recommended by The Maudsley Prescribing Guidelines in Psychiatry (12th edition) in combination with clomipramine as an option if other therapies have failed. In combination it is less well tolerated or has a weaker evidence base than formulary options

Recommended dose initially 20mg once daily increased if necessary to maximum of 40mg (20mg in those 65 years or older)

 Drug Safety Update Citalopram and escitalopram: QT interval prolongation

Pack Price
28 tablet £0.66
Pack Price
28 tablet £0.72
30 tablet
Pack Price
28 tablet £0.82
Pack Price
15 ml £3.91
Pack Price
30 capsule £59.63
Pack Price
28 capsule
30 capsule £0.83
Pack Price
30 capsule £1.80
Pack Price
30 capsule £2.16
Pack Price
30 capsule £4.12
Pack Price
28 tablet £3.44
Pack Price
70 ml £2.58
Pack Price
70 ml £12.95
Pack Price
14 tablet
28 tablet £1.06
30 tablet
Pack Price
28 tablet £0.89
30 tablet

An ECG and BP recording should be taken before commencing treatment for people at significant risk of cardiovascular disease

Pack Price
100 capsule
28 capsule £1.28
84 capsule
Pack Price
100 capsule
28 capsule £1.48
84 capsule
Pack Price
100 capsule
28 capsule £1.70
56 capsule

Unlicensed for this indication but recommended by Maudsley

Add 5 - 20mg/day to an SSRI

Plasma concentration monitoring form ONLY for diagnosis of acute poisoning

Pack Price
28 tablet £1.12
Pack Price
28 tablet £1.18
Pack Price
28 tablet £1.29
Pack Price
28 tablet £11.09
Pack Price
28 tablet £78.06
Pack Price
28 tablet £78.06
Pack Price
150 ml £100.72

Unlicensed for this indication but recommended by Maudsley

Add 2-20mg/day to an SSRI

Pack Price
20 tablet £0.59
Pack Price
20 tablet £0.61
6 tablet
60 tablet
Pack Price
60 tablet £1.28
Pack Price
20 tablet
60 tablet £1.55
Pack Price
20 tablet
60 tablet £1.72
Pack Price
28 tablet £3.04
30 tablet
60 tablet
Pack Price
100 ml £4.10
Pack Price
28 tablet £23.86
Pack Price
28 tablet £24.02
Pack Price
28 tablet £44.43
Pack Price
28 tablet £43.49
Pack Price
28 tablet £50.35
Pack Price
28 capsule £2.66
56 capsule
Pack Price
28 capsule £1.77
Pack Price
56 capsule £5.52
Pack Price
28 capsule £2.40
84 capsule

Not licenced for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Pack Price
28 tablet £2.84
30 tablet
Pack Price
28 tablet £1.22
30 tablet
Pack Price
28 tablet £2.77
30 tablet
Pack Price
30 tablet £1.24
6 tablet
Pack Price
30 tablet £1.34
Pack Price
30 tablet £1.79
Pack Price
30 tablet
Pack Price
30 tablet
Pack Price
1 ml

Women of child-bearing potential must use adequate contraception

High potential for withdrawal symptoms, other SSRIs are preferred

Pack Price
28 tablet £9.86
Pack Price
14 tablet
28 tablet
30 tablet £1.27
Pack Price
30 tablet £1.56
Pack Price
28 tablet
30 tablet
Pack Price
150 ml £9.12
Pack Price
28 tablet
56 tablet £1.82
60 tablet
Pack Price
28 tablet
56 tablet £1.87
60 tablet
Pack Price
30 tablet £6.60
Pack Price
28 capsule £5.25
Pack Price
28 tablet
30 tablet £2.60
Pack Price
14 capsule
28 capsule £2.60
30 capsule
Pack Price
28 tablet
30 tablet £3.90
Pack Price
14 capsule
28 capsule £3.90
30 capsule
Pack Price
30 tablet £33.60
Pack Price
28 capsule £47.11
30 capsule

Restricted to initiation by specialists

Not licenced for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Mainly useful in reducing associated anxiety

Only for careful short term use

Pack Price
100 tablet £30.74
60 tablet
Pack Price
100 tablet £28.39
150 tablet
60 tablet
Pack Price
1 ml
150 ml

Restricted to initiation by specialists

Not licenced for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Used to augment an SSRI

Plasma concentration monitoring form ONLY for use before and during pregnancy

Pack Price
14 tablet
21 tablet
30 tablet
42 tablet
56 tablet £1.11
60 tablet
Pack Price
14 tablet
30 tablet
42 tablet
56 tablet £1.41
Pack Price
30 tablet
56 tablet £1.49
Pack Price
30 tablet
56 tablet £2.44
Pack Price
28 tablet £6.03
30 tablet
56 tablet
Pack Price
28 tablet
30 tablet
56 tablet £1.84
Pack Price
56 tablet
Pack Price
30 tablet
56 tablet £3.30

Restricted to initiation by specialist consultants only

Not licenced for this indication but Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

To augment an SSRI

Special warning for use in women of child-bearing potential

Topiramate may cause foetal harm and foetal growth restriction (small for gestational age and low birth weight) when administered to a pregnant woman. The North American Antiepileptic Drug pregnancy registry data for topiramate monotherapy showed an approximate 3-fold higher prevalence of major congenital malformations (4.3%), compared with a reference group not taking AEDs (1.4%). In addition, data from other studies indicate that, compared with monotherapy, there is an increased risk of teratogenic effects associated with the use of AEDs in combination therapy.

Before the initiation of treatment with topiramate in a woman of childbearing potential, pregnancy testing should be performed and a highly effective contraceptive method advised. The patient should be fully informed of the risks related to the use of topiramate during pregnancy.

Pack Price
28 tablet
60 tablet £1.44
Pack Price
28 tablet
60 tablet £1.52
Pack Price
28 tablet
60 tablet £2.35
Pack Price
28 tablet
60 tablet £14.44