Generalised anxiety disorder

Not licensed for this indication but recommended by The Maudsley Prescribing Guidelines in Psychiatry (12th edition) as the most effective SSRI

Recommended dose initially 20mg daily, increased after 3-4 weeks if necessary. Maximum dose 60mg

Pack Price
30 capsule £59.63
Pack Price
28 capsule
30 capsule £0.83
Pack Price
30 capsule £1.80
Pack Price
30 capsule £2.16
Pack Price
30 capsule £4.12
Pack Price
28 tablet £3.44
Pack Price
70 ml £2.58
Pack Price
70 ml £12.95

Not licensed for this indication but recommended by NICE CG113 and The Maudsley Prescribing Guidelines in Psychiatry (12th edition) as the best tolerated SSRI

Recommended dose initially 25mg daily, increased if necessary by increments of 25mg at intervals of at least one week. Maximum dose 200mg.

N.B Do not prescribe 25mg, 150mg or 200mg tablets. 50mg tablets can be halved.

Pack Price
28 tablet £0.89
30 tablet
Pack Price
14 tablet
28 tablet £1.06
30 tablet
Pack Price
30 tablet £6.60
Pack Price
28 capsule £5.25
Pack Price
28 tablet
30 tablet £2.60
Pack Price
14 capsule
28 capsule £2.60
30 capsule
Pack Price
28 tablet
30 tablet £3.90
Pack Price
14 capsule
28 capsule £3.90
30 capsule
Pack Price
30 tablet £33.60
Pack Price
28 capsule £47.11
30 capsule
Pack Price
56 capsule (4 x 14 capsules) £9.95
Pack Price
56 capsule (4 x 14 capsules) £9.95
84 capsule (6 x 14 capsules) £13.95
Pack Price
56 capsule (4 x 14 capsules) £9.95
Pack Price
84 capsule (6 x 14 capsules) £13.95
Pack Price
56 capsule (4 x 14 capsules) £9.95
Pack Price
84 capsule (6 x 14 capsules) £13.95
Pack Price
56 capsule (4 x 14 capsules) £9.95
Pack Price
56 capsule (4 x 14 capsules) £9.95
Pack Price
100 capsule
14 capsule
56 capsule £1.84
84 capsule
Pack Price
21 capsule
56 capsule
84 capsule £1.91
Pack Price
100 capsule
14 capsule
56 capsule £1.81
Pack Price
21 capsule
56 capsule
84 capsule £2.43
Pack Price
100 capsule
14 capsule
56 capsule £2.17
Pack Price
21 capsule
56 capsule
84 capsule £2.93
Pack Price
56 capsule £2.74
Pack Price
56 capsule £3.54

Unlicensed for this indication but recommended by Maudsley

Recommended dose modified release 50 - 300mg

Patients can be initiated on modified release formulation but all patients should be considered for a switched to immediate release once an optimal dose is established (see policy below)

If XL is needed for clinical reasons then prescribe by branded generic: Biquelle® XL, Zaluron® XL, Sondate® XL and Mintreleq® XL have the lowest cost. N.B In East Kent GPs are being advised to switch to Sondate® XL 

Cost effective use of quetiapine

Plasma concentration monitoring form ONLY for diagnosis of acute poisoning

Pack Price
30 tablet
6 tablet
60 tablet £13.84
Pack Price
2 tablet
60 tablet £52.22
Pack Price
2 tablet
60 tablet £61.75
Pack Price
60 tablet £51.30
Pack Price
60 tablet £73.45
Pack Price
60 tablet £67.66
Pack Price
60 tablet £113.10
Pack Price
60 tablet £113.10
Pack Price
60 tablet £170.00
Pack Price
60 tablet £226.20

Unlicensed for this indication but recommended by Maudsley

Dose: 2.5mg - 10mg

Pack Price
28 tablet £27.72
Pack Price
28 tablet £27.72
Pack Price
28 tablet £27.72
Pack Price
28 capsule £2.66
56 capsule
Pack Price
28 capsule £1.77
Pack Price
56 capsule £5.52
Pack Price
28 capsule £2.40
84 capsule

Not licensed for this indication but recommended by The Maudsley Prescribing Guidelines in Psychiatry (12th edition)

Recommended dose initially 15-30mg at bedtime increased within 2-4 weeks according to response. Maximum 45mg daily as a single dose at bedtime or in 2 divided doses

Pack Price
28 tablet £2.84
30 tablet
Pack Price
28 tablet £1.22
30 tablet
Pack Price
28 tablet £2.77
30 tablet
Pack Price
30 tablet £1.24
6 tablet
Pack Price
30 tablet £1.34
Pack Price
30 tablet £1.79
Pack Price
30 tablet
Pack Price
30 tablet
Pack Price
1 ml

Women of child-bearing potential must use adequate contraception

High potential for withdrawal symptoms, other SSRIs are preferred

Pack Price
28 tablet £9.86
Pack Price
14 tablet
28 tablet
30 tablet £1.27
Pack Price
30 tablet £1.56
Pack Price
28 tablet
30 tablet
Pack Price
150 ml £9.12

Restricted to initiation by specialists

GPs not obliged to prescribe, please check with surgery

Not licensed for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Requires monitoring of liver enzymes and patient should be given a patient alert card. Access the alert card and prescriber information about liver function monitoring here.

Pack Price
28 tablet £30.00

Restricted to initiation by specialists

Not licensed for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Pack Price
100 tablet
20 tablet
30 tablet £7.07
90 tablet
Pack Price
30 tablet £8.30
60 tablet
90 tablet

Restricted to initiation by specialists

Not licensed for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

An ECG and BP recording should be taken before commencing treatment for people at significant risk of cardiovascular disease

Recommended dose initially 25mg daily (ELDERLY 10mg daily) increased over 2 weeks to 100mg - 150mg daily, maximum dose 250mg daily

Pack Price
100 capsule
28 capsule £1.28
84 capsule
Pack Price
100 capsule
28 capsule £1.48
84 capsule
Pack Price
100 capsule
28 capsule £1.70
56 capsule

Restricted to initiation by specialists

Not licenced for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Pack Price
84 tablet £1.20
Pack Price
25 tablet
28 tablet £0.62

Restricted to initiation by specialists

Not licensed for this indication but the Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

An ECG and BP recording should be taken before commencing treatment for people at significant risk of cardiovascular disease

Pack Price
250 tablet
28 tablet £0.92
Pack Price
100 tablet
28 tablet £0.91
500 tablet
84 tablet
Pack Price
150 ml £42.00

Restricted to initiation by specialists

Not licenced for this indication but Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Patient must be informed of dietary restrictions and drug interactions (see SPC and / or BNF for details)

Pack Price
100 tablet
30 tablet £22.10
Pack Price
30 tablet £13.99
60 tablet

Restricted to initiation by specialists

Not licenced for this indication but Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Patient must be informed of dietary restrictions and drug interactions (see SPC and / or BNF for details)

Phenelzine 15mg tablets are not available, click here for more information

Pack Price
100 tablet £22.50

Restricted to initiation by specialists

Not licenced for this indication but Maudsley Prescribing Guidelines in Psychiatry (12th edition) list as an option if other therapies have failed. It is less well tolerated or has a weaker evidence base than formulary options

Useful for somatic symptoms, particularly tachycardia

Pack Price
100 tablet
28 tablet £0.88